Clik here to view.
Next Generation Sequencing: Current realities in cancer biology
The rate of progress in molecular cell biological sciences has become dramatic. This is fuelled in part by developments in technology, none more so than in the field of nucleic acid sequencing....
View ArticleClik here to view.
Genomics / Sequencing supplement 2011
In this Genomics / Sequencing supplement: NGS powers up drug discovery and healthcare (Bhupinder Bhullar, Novartis Pharma AG) Impact of novel sequencing technology on transcriptome analysis (Wei Chen,...
View ArticleClik here to view.
DNA sequencing technologies and emerging applications in drug discovery
In recent years, the development of Next Generation DNA Sequencing (NGS) technology has significantly impacted molecular biology research, resulting in many new insights and discoveries. NGS technology...
View ArticleClik here to view.
Future trends in drug discovery technology
The average cost to a major pharmaceutical company of developing a new drug is over USD 6 billion1. Herper1 observes that the pharmaceutical industry is gripped by rising failure rates and costs, and...
View ArticleClik here to view.
Next generation sequencing: Using RNAseq to identify anti-cancer targets in...
It is possible to attack the vasculature within solid tumours and achieve an anti-cancer effect. In the last decade, a number of studies have utilised cDNA libraries, SAGE analysis and microarrays to...
View ArticleClik here to view.
Next generation sequencing: Application of next generation sequencing to...
Preclinical cancer models allow us to gain insight into therapeutic potential and mechanism of anti-cancer agents early in the drug discovery process. Whilst traditional array-based approaches have...
View ArticleClik here to view.
Understanding early mouse embryonic development using single-cell mRNA...
René Dirks, Department of Molecular Biology, Radboud Institute for Molecular Life Sciences (RIMLS) Biomedical research often involves the use of cell lines that can be cultured in a laboratory....
View ArticleClik here to view.
Next-generation transcriptomic analysis in cancer vascular research
Over the past decade significant advances have been made in the fields of genomic and transcriptomic profiling, inspired by the advent of next-generation sequencing (NGS). Yet despite the considerable...
View ArticleClik here to view.
NEB® launches new NEBNext® Ultra™ II Kit for NGS Library Preparation with as...
New England Biolabs® (NEB) announced the release of the NEBNext Ultra II DNA Library Prep Kit for Illumina® next generation sequencing systems. The new Ultra II kit substantially improves upon its...
View ArticleClik here to view.
Democratising the Data-Driven Medicine revolution
The Data-Driven Medicine revolution is under way. Every day, hospitals and laboratories across the world produce and analyse genomic data from patients with chronic conditions, or at risk of developing...
View Article